1xva: Difference between revisions

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{{Seed}}
[[Image:1xva.png|left|200px]]


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==METHYLTRANSFERASE==
The line below this paragraph, containing "STRUCTURE_1xva", creates the "Structure Box" on the page.
<StructureSection load='1xva' size='340' side='right'caption='[[1xva]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XVA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
{{STRUCTURE_1xva|  PDB=1xva  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xva OCA], [https://pdbe.org/1xva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xva RCSB], [https://www.ebi.ac.uk/pdbsum/1xva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xva ProSAT]</span></td></tr>
 
</table>
===METHYLTRANSFERASE===
== Function ==
 
[https://www.uniprot.org/uniprot/GNMT_RAT GNMT_RAT] Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
 
== Evolutionary Conservation ==
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xv/1xva_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_8810903}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1XVA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XVA OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xva ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Crystal structure of glycine N-methyltransferase from rat liver., Fu Z, Hu Y, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F, Biochemistry. 1996 Sep 17;35(37):11985-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8810903 8810903]
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Glycine N-methyltransferase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Fu Z]]
[[Category: Fu, Z.]]
[[Category: Fujioka M]]
[[Category: Fujioka, M.]]
[[Category: Gomi T]]
[[Category: Gomi, T.]]
[[Category: Hu Y]]
[[Category: Hu, Y.]]
[[Category: Konishi K]]
[[Category: Konishi, K.]]
[[Category: Ogawa H]]
[[Category: Ogawa, H.]]
[[Category: Takata Y]]
[[Category: Takata, Y.]]
[[Category: Takusagawa F]]
[[Category: Takusagawa, F.]]
[[Category: Methyltransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:08:43 2008''

Latest revision as of 11:53, 14 February 2024

METHYLTRANSFERASEMETHYLTRANSFERASE

Structural highlights

1xva is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GNMT_RAT Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1xva, resolution 2.20Å

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