1k38: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1k38.jpg|left|200px]]<br /><applet load="1k38" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1k38, resolution 1.50&Aring;" />
-'''CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-2'''<br />
-==About this Structure==
+==CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-2==
-K38 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with FMT as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1K38 OCA].
+<StructureSection load='1k38' size='340' side='right'caption='[[1k38]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-[[Category: Beta-lactamase]]
+== Structural highlights ==
-[[Category: Salmonella typhimurium]]
+<table><tr><td colspan='2'>[[1k38]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K38 FirstGlance]. <br>
-[[Category: Single protein]]
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-[[Category: Bouillenne, F.]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
-[[Category: Charlier, P.]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k38 OCA], [https://pdbe.org/1k38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k38 RCSB], [https://www.ebi.ac.uk/pdbsum/1k38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k38 ProSAT]</span></td></tr>
-[[Category: Fonze, E.]]
+</table>
-[[Category: Frere, J.M.]]
+== Function ==
-[[Category: Kerff, F.]]
+[https://www.uniprot.org/uniprot/BLO2_SALTM BLO2_SALTM] This is an oxacillin-hydrolyzing beta-lactamase.
-[[Category: FMT]]
+== Evolutionary Conservation ==
-[[Category: antibiotic resistance]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: carbamylated lysine]]
+Check<jmol>
-[[Category: hydrolase]]
+  <jmolCheckbox>
-[[Category: serine beta-lactamase]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k3/1k38_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k38 ConSurf].
+<div style="clear:both"></div>
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 18:48:53 2007''
+==See Also==
+*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
+[[Category: Bouillenne F]]
+[[Category: Charlier P]]
+[[Category: Fonze E]]
+[[Category: Frere JM]]
+[[Category: Kerff F]]