163d: Difference between revisions

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OCA

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-'''Theoretical Model'''
+{{Theoretical_model}}
-The entry 163D is a Theoretical Model titled 'A THREE-DIMENSIONAL MODEL OF THE REV BINDING ELEMENT OF HIV-1 DERIVED FROM ANALYSES OF IN VITRO SELECTED VARIANTS'.
+==A THREE-DIMENSIONAL MODEL OF THE REV BINDING ELEMENT OF HIV- 1 DERIVED FROM ANALYSES OF IN VITRO SELECTED VARIANTS==
+<StructureSection load='163d' size='340' side='right'caption='[[163d]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=163D FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=163d FirstGlance], [https://www.ebi.ac.uk/pdbsum/163d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=163d ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Coordinated variations in the sequence of the Rev-binding element of HIV-1, identified by in vitro genetic selections, have been used as distance and conformational constraints for molecular modelling. Three-dimensional models of the wild-type Rev-binding element and several, evolved RNA ligands (aptamers) have been constructed. These models demonstrate that non-Watson-Crick pairings open the major groove allowing access of an alpha-helical peptide from Rev, and explain why some selected RNA sequences can bind Rev more tightly than others.
+A three-dimensional model of the Rev-binding element of HIV-1 derived from analyses of aptamers.,Leclerc F, Cedergren R, Ellington AD Nat Struct Biol. 1994 May;1(5):293-300. PMID:7664035<ref>PMID:7664035</ref>
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 13:06:36 2008''
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 163d" style="background-color:#fffaf0;"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Theoretical Model]]
+[[Category: Large Structures]]
+[[Category: Cedergren, R J]]
+[[Category: Ellington, A D]]
+[[Category: Leclerc, F]]