1j4g: Difference between revisions

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New page: left|200px<br /><applet load="1j4g" size="450" color="white" frame="true" align="right" spinBox="true" caption="1j4g, resolution 2.0Å" /> '''crystal structure ana...
 
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[[Image:1j4g.jpg|left|200px]]<br /><applet load="1j4g" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1j4g, resolution 2.0&Aring;" />
'''crystal structure analysis of the trichosanthin delta C7'''<br />


==About this Structure==
==crystal structure analysis of the trichosanthin delta C7==
1J4G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii] with CA as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1J4G OCA].  
<StructureSection load='1j4g' size='340' side='right'caption='[[1j4g]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1j4g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J4G FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j4g OCA], [https://pdbe.org/1j4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j4g RCSB], [https://www.ebi.ac.uk/pdbsum/1j4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j4g ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RIPT_TRIKI RIPT_TRIKI] Inactivates eukaryotic 60S ribosomal subunits.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/1j4g_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j4g ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trichosanthes kirilowii]]
[[Category: Trichosanthes kirilowii]]
[[Category: rRNA N-glycosylase]]
[[Category: Ding Y]]
[[Category: Ding, Y.]]
[[Category: Dong YC]]
[[Category: Dong, Y.C.]]
[[Category: Liu YW]]
[[Category: Liu, Y.W.]]
[[Category: Rao ZH]]
[[Category: Rao, Z.H.]]
[[Category: Shaw PC]]
[[Category: Shaw, P.C.]]
[[Category: Too HM]]
[[Category: Too, H.M.]]
[[Category: Wang ZL]]
[[Category: Wang, Z.L.]]
[[Category: CA]]
[[Category: antiviral]]
[[Category: protein synthesis inhibitor]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 17:55:42 2007''

Latest revision as of 21:12, 29 May 2024

crystal structure analysis of the trichosanthin delta C7crystal structure analysis of the trichosanthin delta C7

Structural highlights

1j4g is a 4 chain structure with sequence from Trichosanthes kirilowii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RIPT_TRIKI Inactivates eukaryotic 60S ribosomal subunits.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1j4g, resolution 2.00Å

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