2vor: Difference between revisions

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-{{Seed}}
-[[Image:2vor.jpg|left|200px]]
-<!--
+==Crystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCP==
-The line below this paragraph, containing "STRUCTURE_2vor", creates the "Structure Box" on the page.
+<StructureSection load='2vor' size='340' side='right'caption='[[2vor]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2vor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOR FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-{{STRUCTURE_2vor|  PDB=2vor  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vor OCA], [https://pdbe.org/2vor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vor RCSB], [https://www.ebi.ac.uk/pdbsum/2vor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vor ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/O53174_MYCTO O53174_MYCTO]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/2vor_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vor ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURES OF MYCOBACTERIUM TUBERCULOSIS FOLYLPOLYGLUTAMATE SYNTHASE COMPLEXED WITH ADP AND AMPPCP===
+==See Also==
+*[[Folylpolyglutamate synthase|Folylpolyglutamate synthase]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_18566510}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 18566510 is the PubMed ID number.
+[[Category: Mycobacterium tuberculosis H37Rv]]
--->
+[[Category: Baker EN]]
-{{ABSTRACT_PUBMED_18566510}}
+[[Category: Metcalf P]]
+[[Category: Smith CA]]
-==About this Structure==
+[[Category: Young PG]]
-VOR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOR OCA].
-==Reference==
-Structures of Mycobacterium tuberculosisfolylpolyglutamate synthase complexed with ADP and AMPPCP., Young PG, Smith CA, Metcalf P, Baker EN, Acta Crystallogr D Biol Crystallogr. 2008 Jul;64(Pt 7):745-53. Epub 2008, Jun 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18566510 18566510]
-[[Category: Mycobacterium tuberculosis]]
-[[Category: Single protein]]
-[[Category: Tetrahydrofolate synthase]]
-[[Category: Baker, E N.]]
-[[Category: Metcalf, P.]]
-[[Category: Smith, C A.]]
-[[Category: Young, P G.]]
-[[Category: Atp-binding]]
-[[Category: Cell cycle]]
-[[Category: Cell division]]
-[[Category: Cell shape]]
-[[Category: Cell wall biogenesis/degradation]]
-[[Category: Cobalt binding]]
-[[Category: Conformational change]]
-[[Category: Folate metabolism]]
-[[Category: Ligase]]
-[[Category: Nucleotide binding]]
-[[Category: Nucleotide-binding]]
-[[Category: Peptidoglycan synthesis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 11:23:23 2008''