1mix: Difference between revisions

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-{{Seed}}
-[[Image:1mix.png|left|200px]]
-<!--
+==Crystal structure of a FERM domain of Talin==
-The line below this paragraph, containing "STRUCTURE_1mix", creates the "Structure Box" on the page.
+<StructureSection load='1mix' size='340' side='right'caption='[[1mix]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1mix]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIX FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mix OCA], [https://pdbe.org/1mix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mix RCSB], [https://www.ebi.ac.uk/pdbsum/1mix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mix ProSAT]</span></td></tr>
-{{STRUCTURE_1mix|  PDB=1mix  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mix_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mix ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of a FERM domain of Talin===
+==See Also==
+*[[Talin 3D structures|Talin 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_12535520}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 12535520 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_12535520}}
-==About this Structure==
-MIX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIX OCA].
-==Reference==
-Structural determinants of integrin recognition by talin., Garcia-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC, Mol Cell. 2003 Jan;11(1):49-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12535520 12535520]
 [[Category: Gallus gallus]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Calderwood, D A.]]
+[[Category: Calderwood DA]]
-[[Category: Campbell, I D.]]
+[[Category: Campbell ID]]
-[[Category: Critchley, D.]]
+[[Category: Critchley D]]
-[[Category: Garcia-Alvarez, B.]]
+[[Category: Garcia-Alvarez B]]
-[[Category: Ginsberg, M H.]]
+[[Category: Ginsberg MH]]
-[[Category: Liddington, R C.]]
+[[Category: Liddington RC]]
-[[Category: Pereda, J M.de.]]
+[[Category: Ulmer TS]]
-[[Category: Ulmer, T S.]]
+[[Category: De Pereda JM]]
-[[Category: Cytoskeleton]]
-[[Category: Ferm domain]]
-[[Category: Focal adhesion]]
-[[Category: Integrin binding]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 00:04:28 2008''