1mih: Difference between revisions

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-{{Seed}}
-[[Image:1mih.png|left|200px]]
-<!--
+==A ROLE FOR CHEY GLU 89 IN CHEZ-MEDIATED DEPHOSPHORYLATION OF THE E. COLI CHEMOTAXIS RESPONSE REGULATOR CHEY==
-The line below this paragraph, containing "STRUCTURE_1mih", creates the "Structure Box" on the page.
+<StructureSection load='1mih' size='340' side='right'caption='[[1mih]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1mih]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIH FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_1mih|  PDB=1mih  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mih OCA], [https://pdbe.org/1mih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mih RCSB], [https://www.ebi.ac.uk/pdbsum/1mih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mih ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CHEY_ECOLI CHEY_ECOLI] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.<ref>PMID:20346719</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mih_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mih ConSurf].
+<div style="clear:both"></div>
-===A ROLE FOR CHEY GLU 89 IN CHEZ-MEDIATED DEPHOSPHORYLATION OF THE E. COLI CHEMOTAXIS RESPONSE REGULATOR CHEY===
+==See Also==
+*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_12591865}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 12591865 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_12591865}}
-==About this Structure==
-MIH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIH OCA].
-==Reference==
-CheZ-mediated dephosphorylation of the Escherichia coli chemotaxis response regulator CheY: role for CheY glutamate 89., Silversmith RE, Guanga GP, Betts L, Chu C, Zhao R, Bourret RB, J Bacteriol. 2003 Mar;185(5):1495-502. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12591865 12591865]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Betts, L.]]
+[[Category: Betts L]]
-[[Category: Bourret, R B.]]
+[[Category: Bourret RB]]
-[[Category: Chu, C.]]
+[[Category: Chu C]]
-[[Category: Guanga, G P.]]
+[[Category: Guanga GP]]
-[[Category: Silversmith, R E.]]
+[[Category: Silversmith RE]]
-[[Category: Zhao, R.]]
+[[Category: Zhao R]]
-[[Category: Bacterial chemotaxis]]
-[[Category: Dephosphorylation]]
-[[Category: Response regulator]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 00:02:38 2008''