1mhh: Difference between revisions

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[[Image:1mhh.png|left|200px]]


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==Structure of P. magnus protein L mutant bound to a mouse Fab==
The line below this paragraph, containing "STRUCTURE_1mhh", creates the "Structure Box" on the page.
<StructureSection load='1mhh' size='340' side='right'caption='[[1mhh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mhh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Finegoldia_magna_ATCC_29328 Finegoldia magna ATCC 29328] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MHH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AEA:(2-AMINO-2-CARBAMOYL-ETHYLSULFANYL)-ACETIC+ACID'>AEA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
{{STRUCTURE_1mhh| PDB=1mhh |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mhh OCA], [https://pdbe.org/1mhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mhh RCSB], [https://www.ebi.ac.uk/pdbsum/1mhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mhh ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/1mhh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mhh ConSurf].
<div style="clear:both"></div>


===Antibody-antigen complex===
==See Also==
 
*[[Antibody 3D structures|Antibody 3D structures]]
 
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12221088}}, adds the Publication Abstract to the page
</StructureSection>
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[[Category: Finegoldia magna ATCC 29328]]
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_12221088}}
[[Category: Mus musculus]]
 
[[Category: Graille M]]
==About this Structure==
[[Category: Stura EA]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MHH OCA].
 
==Reference==
Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface., Graille M, Harrison S, Crump MP, Findlow SC, Housden NG, Muller BH, Battail-Poirot N, Sibai G, Sutton BJ, Taussig MJ, Jolivet-Reynaud C, Gore MG, Stura EA, J Biol Chem. 2002 Dec 6;277(49):47500-6. Epub 2002 Sep 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12221088 12221088]
[[Category: Graille, M.]]
[[Category: Stura, E A.]]
[[Category: Antibody-antigen complex]]
[[Category: B cell superantigen]]
[[Category: Immunoglobulin binding protein]]
 
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