1i2a: Difference between revisions

New page: left|200px<br /><applet load="1i2a" size="450" color="white" frame="true" align="right" spinBox="true" caption="1i2a, resolution 1.85Å" /> '''CRYSTAL STRUCTURE OF...
 
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[[Image:1i2a.gif|left|200px]]<br /><applet load="1i2a" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1i2a, resolution 1.85&Aring;" />
'''CRYSTAL STRUCTURE OF L1 RIBOSOMAL PROTEIN FROM METHANOCOCCUS JANNASCHII WITH 1.85A RESOLUTION.'''<br />


==About this Structure==
==CRYSTAL STRUCTURE OF L1 RIBOSOMAL PROTEIN FROM METHANOCOCCUS JANNASCHII WITH 1.85A RESOLUTION.==
1I2A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with PTL as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1I2A OCA].  
<StructureSection load='1i2a' size='340' side='right'caption='[[1i2a]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1i2a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2A FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTL:PENTANAL'>PTL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2a OCA], [https://pdbe.org/1i2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2a RCSB], [https://www.ebi.ac.uk/pdbsum/1i2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL1_METJA RL1_METJA] Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.  Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i2a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i2a ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ribosomal protein L1|Ribosomal protein L1]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Single protein]]
[[Category: Nikonov SV]]
[[Category: Nikonov, S.V.]]
[[Category: Smolinskaya Y]]
[[Category: Smolinskaya, Y.]]
[[Category: PTL]]
[[Category: primary rrna-binding protein]]
[[Category: ribosomal protein]]
[[Category: translational repressor]]
 
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