1jk0: Difference between revisions

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[[Image:1jk0.png|left|200px]]


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==Ribonucleotide reductase Y2Y4 heterodimer==
The line below this paragraph, containing "STRUCTURE_1jk0", creates the "Structure Box" on the page.
<StructureSection load='1jk0' size='340' side='right'caption='[[1jk0]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1jk0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JK0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1jk0| PDB=1jk0 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jk0 OCA], [https://pdbe.org/1jk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jk0 RCSB], [https://www.ebi.ac.uk/pdbsum/1jk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jk0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RIR4_YEAST RIR4_YEAST] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RNR4 is required for proper folding of RNR2 and assembly with the large subunits.<ref>PMID:10535923</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/1jk0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jk0 ConSurf].
<div style="clear:both"></div>


===Ribonucleotide reductase Y2Y4 heterodimer===
==See Also==
 
*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
 
== References ==
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_11526233}}
 
==About this Structure==
1JK0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JK0 OCA].
 
==Reference==
Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer., Voegtli WC, Ge J, Perlstein DL, Stubbe J, Rosenzweig AC, Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10073-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11526233 11526233]
[[Category: Protein complex]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Ge, J.]]
[[Category: Ge J]]
[[Category: Perlstein, D L.]]
[[Category: Perlstein DL]]
[[Category: Rosenzweig, A C.]]
[[Category: Rosenzweig AC]]
[[Category: Stubbe, J.]]
[[Category: Stubbe J]]
[[Category: Voegtli, W C.]]
[[Category: Voegtli WC]]
[[Category: R2]]
[[Category: Ribonucleotide reductase]]
 
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