1hnc: Difference between revisions

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-{{Seed}}
-[[Image:1hnc.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY==
-The line below this paragraph, containing "STRUCTURE_1hnc", creates the "Structure Box" on the page.
+<StructureSection load='1hnc' size='340' side='right'caption='[[1hnc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1hnc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HNC FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDN:GLUTATHIONE+S-(2,4+DINITROBENZENE)'>GDN</scene></td></tr>
-{{STRUCTURE_1hnc|  PDB=1hnc  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hnc OCA], [https://pdbe.org/1hnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hnc RCSB], [https://www.ebi.ac.uk/pdbsum/1hnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hnc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GSTM2_HUMAN GSTM2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16549767</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hn/1hnc_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hnc ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY===
+==See Also==
+*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_8182750}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 8182750 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_8182750}}
-==About this Structure==
-HNC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HNC OCA].
-==Reference==
-Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity., Raghunathan S, Chandross RJ, Kretsinger RH, Allison TJ, Penington CJ, Rule GS, J Mol Biol. 1994 May 20;238(5):815-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8182750 8182750]
-[[Category: Glutathione transferase]]
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Allison, T J.]]
+[[Category: Allison TJ]]
-[[Category: Chandross, R J.]]
+[[Category: Chandross RJ]]
-[[Category: Kretsinger, R H.]]
+[[Category: Kretsinger RH]]
-[[Category: Penington, C J.]]
+[[Category: Penington CJ]]
-[[Category: Raghunathan, S.]]
+[[Category: Raghunathan S]]
-[[Category: Rule, G S.]]
+[[Category: Rule GS]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 08:25:44 2008''