1fwk: Difference between revisions

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-{{Seed}}
-[[Image:1fwk.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP==
-The line below this paragraph, containing "STRUCTURE_1fwk", creates the "Structure Box" on the page.
+<StructureSection load='1fwk' size='340' side='right'caption='[[1fwk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1fwk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FWK FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_1fwk|  PDB=1fwk  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fwk OCA], [https://pdbe.org/1fwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fwk RCSB], [https://www.ebi.ac.uk/pdbsum/1fwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fwk ProSAT]</span></td></tr>
+</table>
-===CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP===
+== Function ==
+[https://www.uniprot.org/uniprot/KHSE_METJA KHSE_METJA] Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate (By similarity).
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_11188689}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 11188689 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/1fwk_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_11188689}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-FWK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FWK OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fwk ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily., Zhou T, Daugherty M, Grishin NV, Osterman AL, Zhang H, Structure. 2000 Dec 15;8(12):1247-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11188689 11188689]
+</StructureSection>
-[[Category: Homoserine kinase]]
+[[Category: Large Structures]]
 [[Category: Methanocaldococcus jannaschii]]
-[[Category: Single protein]]
+[[Category: Daugherty M]]
-[[Category: Daugherty, M.]]
+[[Category: Grishin NV]]
-[[Category: Grishin, N V.]]
+[[Category: Osterman AL]]
-[[Category: Osterman, A L.]]
+[[Category: Zhang H]]
-[[Category: Zhang, H.]]
+[[Category: Zhou T]]
-[[Category: Zhou, T.]]
-[[Category: Kinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:03:08 2008''