1en6: Difference between revisions

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-{{Seed}}
-[[Image:1en6.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146L MUTANT==
-The line below this paragraph, containing "STRUCTURE_1en6", creates the "Structure Box" on the page.
+<StructureSection load='1en6' size='340' side='right'caption='[[1en6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1en6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EN6 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-{{STRUCTURE_1en6|  PDB=1en6  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1en6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1en6 OCA], [https://pdbe.org/1en6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1en6 RCSB], [https://www.ebi.ac.uk/pdbsum/1en6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1en6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1en6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1en6 ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146L MUTANT===
+==See Also==
+*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_11141052}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 11141052 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_11141052}}
-==About this Structure==
-EN6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN6 OCA].
-==Reference==
-Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase., Edwards RA, Whittaker MM, Whittaker JW, Baker EN, Jameson GB, Biochemistry. 2001 Jan 9;40(1):15-27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11141052 11141052]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Superoxide dismutase]]
+[[Category: Baker EN]]
-[[Category: Baker, E N.]]
+[[Category: Edwards RA]]
-[[Category: Edwards, R A.]]
+[[Category: Jameson GB]]
-[[Category: Jameson, G B.]]
+[[Category: Whittaker JW]]
-[[Category: Whittaker, J W.]]
+[[Category: Whittaker MM]]
-[[Category: Whittaker, M M.]]
-[[Category: Manganese superoxide dismutase]]
-[[Category: Mutant]]
-[[Category: Proton shuttle]]
-[[Category: Q146l]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:01:47 2008''