1eli: Difference between revisions

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-{{Seed}}
-[[Image:1eli.png|left|200px]]
-<!--
+==COMPLEX OF MONOMERIC SARCOSINE OXIDASE WITH THE INHIBITOR PYRROLE-2-CARBOXYLATE==
-The line below this paragraph, containing "STRUCTURE_1eli", creates the "Structure Box" on the page.
+<StructureSection load='1eli' size='340' side='right'caption='[[1eli]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1eli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._B-0618 Bacillus sp. B-0618]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ELI FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PYC:PYRROLE-2-CARBOXYLATE'>PYC</scene></td></tr>
-{{STRUCTURE_1eli|  PDB=1eli  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eli OCA], [https://pdbe.org/1eli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eli RCSB], [https://www.ebi.ac.uk/pdbsum/1eli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eli ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MSOX_BACB0 MSOX_BACB0] Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L-alanine.[HAMAP-Rule:MF_00516]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/1eli_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eli ConSurf].
+<div style="clear:both"></div>
-===COMPLEX OF MONOMERIC SARCOSINE OXIDASE WITH THE INHIBITOR PYRROLE-2-CARBOXYLATE===
+==See Also==
+*[[Sarcosine oxidase|Sarcosine oxidase]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_10913292}}, adds the Publication Abstract to the page
+[[Category: Bacillus sp. B-0618]]
-(as it appears on PubMed at http://www.pubmed.gov), where 10913292 is the PubMed ID number.
+[[Category: Large Structures]]
--->
+[[Category: Chen Z-W]]
-{{ABSTRACT_PUBMED_10913292}}
+[[Category: Jorns MS]]
+[[Category: Mathews FS]]
-==About this Structure==
+[[Category: Trickey P]]
-ELI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELI OCA].
+[[Category: Wagner MA]]
-==Reference==
-Monomeric sarcosine oxidase: 1. Flavin reactivity and active site binding determinants., Wagner MA, Trickey P, Chen ZW, Mathews FS, Jorns MS, Biochemistry. 2000 Aug 1;39(30):8813-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10913292 10913292]
-[[Category: Bacillus sp.]]
-[[Category: Sarcosine oxidase]]
-[[Category: Single protein]]
-[[Category: Chen, Z W.]]
-[[Category: Jorns, M S.]]
-[[Category: Mathews, F S.]]
-[[Category: Trickey, P.]]
-[[Category: Wagner, M A.]]
-[[Category: Flavoprotein]]
-[[Category: Oxidase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:56:20 2008''