1egp: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1egp.png|left|200px]]


<!--
==PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER==
The line below this paragraph, containing "STRUCTURE_1egp", creates the "Structure Box" on the page.
<StructureSection load='1egp' size='340' side='right'caption='[[1egp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1egp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EGP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1egp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1egp OCA], [https://pdbe.org/1egp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1egp RCSB], [https://www.ebi.ac.uk/pdbsum/1egp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1egp ProSAT]</span></td></tr>
{{STRUCTURE_1egp|  PDB=1egp |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/ICIC_HIRME ICIC_HIRME] Inhibits both elastase and cathepsin G.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/1egp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1egp ConSurf].
<div style="clear:both"></div>


===PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER===
==See Also==
 
*[[Eglin|Eglin]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_8425603}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8425603 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_8425603}}
 
==About this Structure==
1EGP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EGP OCA].
 
==Reference==
Structure of the proteinase inhibitor eglin c with hydrolysed reactive centre at 2.0 A resolution., Betzel C, Dauter Z, Genov N, Lamzin V, Navaza J, Schnebli HP, Visanji M, Wilson KS, FEBS Lett. 1993 Feb 15;317(3):185-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8425603 8425603]
[[Category: Hirudo medicinalis]]
[[Category: Hirudo medicinalis]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Betzel, C.]]
[[Category: Betzel C]]
[[Category: Dauter, Z.]]
[[Category: Dauter Z]]
[[Category: Lamzin, V.]]
[[Category: Lamzin V]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
[[Category: Proteinase inhibitor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:40:20 2008''

Latest revision as of 10:02, 7 February 2024

PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTERPROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER

Structural highlights

1egp is a 2 chain structure with sequence from Hirudo medicinalis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ICIC_HIRME Inhibits both elastase and cathepsin G.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1egp, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1egp&oldid=4042557"