1edz: Difference between revisions

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-{{Seed}}
-[[Image:1edz.png|left|200px]]
-<!--
+==STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE==
-The line below this paragraph, containing "STRUCTURE_1edz", creates the "Structure Box" on the page.
+<StructureSection load='1edz' size='340' side='right'caption='[[1edz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1edz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EDZ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1edz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1edz OCA], [https://pdbe.org/1edz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1edz RCSB], [https://www.ebi.ac.uk/pdbsum/1edz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1edz ProSAT]</span></td></tr>
-{{STRUCTURE_1edz|  PDB=1edz  |  SCENE=  }}
+</table>
+== Function ==
-===STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE===
+[https://www.uniprot.org/uniprot/MTD1_YEAST MTD1_YEAST] Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
-<!--
+Check<jmol>
-The line below this paragraph, {{ABSTRACT_PUBMED_10933503}}, adds the Publication Abstract to the page
+  <jmolCheckbox>
-(as it appears on PubMed at http://www.pubmed.gov), where 10933503 is the PubMed ID number.
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/1edz_consurf.spt"</scriptWhenChecked>
--->
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-{{ABSTRACT_PUBMED_10933503}}
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
-==About this Structure==
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1edz ConSurf].
-EDZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EDZ OCA].
+<div style="clear:both"></div>
+__TOC__
-==Reference==
+</StructureSection>
-The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae., Monzingo AF, Breksa A, Ernst S, Appling DR, Robertus JD, Protein Sci. 2000 Jul;9(7):1374-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10933503 10933503]
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Single protein]]
+[[Category: Appling DR]]
-[[Category: Appling, D R.]]
+[[Category: Breksa A]]
-[[Category: Breksa, A.]]
+[[Category: Ernst S]]
-[[Category: Ernst, S.]]
+[[Category: Monzingo AF]]
-[[Category: Monzingo, A F.]]
+[[Category: Robertus JD]]
-[[Category: Robertus, J D.]]
-[[Category: Dehydrogenase]]
-[[Category: Folate]]
-[[Category: Monofunctional]]
-[[Category: Nucleotide-binding domain]]
-[[Category: Oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:33:05 2008''