1ec7: Difference between revisions

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-{{Seed}}
-[[Image:1ec7.png|left|200px]]
-<!--
+==E. COLI GLUCARATE DEHYDRATASE NATIVE ENZYME==
-The line below this paragraph, containing "STRUCTURE_1ec7", creates the "Structure Box" on the page.
+<StructureSection load='1ec7' size='340' side='right'caption='[[1ec7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1ec7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EC7 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_1ec7|  PDB=1ec7  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ec7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ec7 OCA], [https://pdbe.org/1ec7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ec7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ec7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ec7 ProSAT]</span></td></tr>
+</table>
-===E. COLI GLUCARATE DEHYDRATASE NATIVE ENZYME===
+== Function ==
+[https://www.uniprot.org/uniprot/GUDD_ECOLI GUDD_ECOLI] Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D-glucarate (5-kdGluc). Also acts on L-idarate.
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_10769114}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 10769114 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/1ec7_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_10769114}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-EC7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EC7 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ec7 ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli., Gulick AM, Hubbard BK, Gerlt JA, Rayment I, Biochemistry. 2000 Apr 25;39(16):4590-602. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10769114 10769114]
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Glucarate dehydratase]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Gerlt JA]]
-[[Category: Gerlt, J A.]]
+[[Category: Gulick AM]]
-[[Category: Gulick, A M.]]
+[[Category: Hubbard BK]]
-[[Category: Hubbard, B K.]]
+[[Category: Rayment I]]
-[[Category: Rayment, I.]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:28:54 2008''