1e2a: Difference between revisions

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[[Image:1e2a.png|left|200px]]


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==ENZYME IIA FROM THE LACTOSE SPECIFIC PTS FROM LACTOCOCCUS LACTIS==
The line below this paragraph, containing "STRUCTURE_1e2a", creates the "Structure Box" on the page.
<StructureSection load='1e2a' size='340' side='right'caption='[[1e2a]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1e2a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E2A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1e2a|  PDB=1e2a  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e2a OCA], [https://pdbe.org/1e2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e2a RCSB], [https://www.ebi.ac.uk/pdbsum/1e2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e2a ProSAT]</span></td></tr>
 
</table>
===ENZYME IIA FROM THE LACTOSE SPECIFIC PTS FROM LACTOCOCCUS LACTIS===
== Function ==
 
[https://www.uniprot.org/uniprot/PTLA_LACLL PTLA_LACLL] The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_9261069}}, adds the Publication Abstract to the page
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/1e2a_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_9261069}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1E2A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2A OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e2a ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
The structure of enzyme IIAlactose from Lactococcus lactis reveals a new fold and points to possible interactions of a multicomponent system., Sliz P, Engelmann R, Hengstenberg W, Pai EF, Structure. 1997 Jun 15;5(6):775-88. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9261069 9261069]
</StructureSection>
[[Category: Lactococcus lactis]]
[[Category: Lactococcus lactis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Engelmann, R.]]
[[Category: Engelmann R]]
[[Category: Hengstenberg, W.]]
[[Category: Hengstenberg W]]
[[Category: Pai, E F.]]
[[Category: Pai EF]]
[[Category: Sliz, P.]]
[[Category: Sliz P]]
[[Category: Enzyme iia]]
[[Category: Helical bundle]]
[[Category: Phosphotransferase system]]
[[Category: Pt]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:01:36 2008''

Latest revision as of 10:00, 7 February 2024

ENZYME IIA FROM THE LACTOSE SPECIFIC PTS FROM LACTOCOCCUS LACTISENZYME IIA FROM THE LACTOSE SPECIFIC PTS FROM LACTOCOCCUS LACTIS

Structural highlights

1e2a is a 3 chain structure with sequence from Lactococcus lactis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTLA_LACLL The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1e2a, resolution 2.30Å

Drag the structure with the mouse to rotate

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