1bi2: Difference between revisions

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[[Image:1bi2.png|left|200px]]


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==STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR==
The line below this paragraph, containing "STRUCTURE_1bi2", creates the "Structure Box" on the page.
<StructureSection load='1bi2' size='340' side='right'caption='[[1bi2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1bi2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BI2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bi2 OCA], [https://pdbe.org/1bi2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bi2 RCSB], [https://www.ebi.ac.uk/pdbsum/1bi2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bi2 ProSAT]</span></td></tr>
{{STRUCTURE_1bi2| PDB=1bi2 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bi2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bi2 ConSurf].
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===STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR===
==See Also==
 
*[[Diphtheria toxin repressor|Diphtheria toxin repressor]]
 
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{{ABSTRACT_PUBMED_9712865}}
 
==About this Structure==
1BI2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BI2 OCA].
 
==Reference==
Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR., Pohl E, Holmes RK, Hol WG, J Biol Chem. 1998 Aug 28;273(35):22420-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9712865 9712865]
[[Category: Corynebacterium diphtheriae]]
[[Category: Corynebacterium diphtheriae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hol, W G.J.]]
[[Category: Hol WGJ]]
[[Category: Pohl, E.]]
[[Category: Pohl E]]
[[Category: Dna-binding]]
[[Category: Iron]]
[[Category: Repressor]]
[[Category: Transcription regulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:11:52 2008''

Latest revision as of 09:36, 7 February 2024

STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSORSTRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR

Structural highlights

1bi2 is a 2 chain structure with sequence from Corynebacterium diphtheriae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DTXR_CORDI Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1bi2, resolution 2.30Å

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