1awc: Difference between revisions

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{{Seed}}
[[Image:1awc.png|left|200px]]


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==MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA==
The line below this paragraph, containing "STRUCTURE_1awc", creates the "Structure Box" on the page.
<StructureSection load='1awc' size='340' side='right'caption='[[1awc]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1awc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AWC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr>
{{STRUCTURE_1awc|  PDB=1awc  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1awc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1awc OCA], [https://pdbe.org/1awc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1awc RCSB], [https://www.ebi.ac.uk/pdbsum/1awc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1awc ProSAT]</span></td></tr>
 
</table>
===MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA===
== Function ==
 
[https://www.uniprot.org/uniprot/GABPA_MOUSE GABPA_MOUSE] Transcription factor capable of interacting with purine rich repeats (GA repeats).
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_9461436}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aw/1awc_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_9461436}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1AWC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AWC OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1awc ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA., Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C, Science. 1998 Feb 13;279(5353):1037-41. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9461436 9461436]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Batchelor AH]]
[[Category: Batchelor, A H.]]
[[Category: Wolberger C]]
[[Category: Wolberger, C.]]
[[Category: Ankyrin repeat]]
[[Category: Dna-binding]]
[[Category: Ets domain]]
[[Category: Nuclear protein]]
[[Category: Transcription factor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:44:28 2008''

Latest revision as of 09:33, 7 February 2024

MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNAMOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA

Structural highlights

1awc is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.15Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GABPA_MOUSE Transcription factor capable of interacting with purine rich repeats (GA repeats).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1awc, resolution 2.15Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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