2qls: Difference between revisions
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New page: '''Unreleased structure''' The entry 2qls is ON HOLD until Paper Publication Authors: Charles, P., Sundaresan, S., Palani, K., Neeelagandan, K., Ponnuswamy, M.N. Description: crystal s... |
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==crystal structure of hemoglobin from dog (Canis familiaris) at 3.5 Angstrom resolution== | |||
<StructureSection load='2qls' size='340' side='right'caption='[[2qls]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2qls]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QLS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qls OCA], [https://pdbe.org/2qls PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qls RCSB], [https://www.ebi.ac.uk/pdbsum/2qls PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qls ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HBA_CANLF HBA_CANLF] Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.[UniProtKB:P01946] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ql/2qls_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qls ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Canis lupus familiaris]] | |||
[[Category: Large Structures]] | |||
[[Category: Neeelagandan K]] | |||
[[Category: Packianathan C]] | |||
[[Category: Palani K]] | |||
[[Category: Ponnuswamy MN]] | |||
[[Category: Sundaresan S]] | |||
Latest revision as of 16:54, 13 March 2024
crystal structure of hemoglobin from dog (Canis familiaris) at 3.5 Angstrom resolutioncrystal structure of hemoglobin from dog (Canis familiaris) at 3.5 Angstrom resolution
Structural highlights
FunctionHBA_CANLF Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.[UniProtKB:P01946] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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