1bul: Difference between revisions
New page: left|200px<br /><applet load="1bul" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bul, resolution 1.89Å" /> '''6ALPHA-(HYDROXYPROPY... |
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== | ==6ALPHA-(HYDROXYPROPYL)PENICILLANATE ACYLATED ON NMC-A BETA-LACTAMASE FROM ENTEROBACTER CLOACAE== | ||
<StructureSection load='1bul' size='340' side='right'caption='[[1bul]], [[Resolution|resolution]] 1.89Å' scene=''> | |||
[[ | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1bul]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BUL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AP3:2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC+ACID'>AP3</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bul OCA], [https://pdbe.org/1bul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bul RCSB], [https://www.ebi.ac.uk/pdbsum/1bul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bul ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BLAN_ENTCL BLAN_ENTCL] Hydrolyzes carbapenems such as imipenem, which are extended-spectrum beta-lactam antibiotics. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bu/1bul_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bul ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Enterobacter cloacae]] | [[Category: Enterobacter cloacae]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Bulychev | [[Category: Bulychev A]] | ||
[[Category: Miyashita | [[Category: Miyashita K]] | ||
[[Category: Mobashery | [[Category: Mobashery S]] | ||
[[Category: Mourey | [[Category: Mourey L]] | ||
[[Category: Samama | [[Category: Samama JP]] | ||
[[Category: Swaren | [[Category: Swaren P]] | ||
