2z2c: Difference between revisions

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[[Image:2z2c.jpg|left|200px]]


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==MURA inhibited by unag-cnicin adduct==
The line below this paragraph, containing "STRUCTURE_2z2c", creates the "Structure Box" on the page.
<StructureSection load='2z2c' size='340' side='right'caption='[[2z2c]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2z2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z2C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=UDC:2-(ACETYLAMINO)-3-O-[(2S,3S)-2-CARBOXY-3,4-DIHYDROXYBUTAN-2-YL]-2-DEOXY-ALPHA-D-GLUCOPYRANOSE'>UDC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
{{STRUCTURE_2z2c| PDB=2z2c |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2c OCA], [https://pdbe.org/2z2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z2c RCSB], [https://www.ebi.ac.uk/pdbsum/2z2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z2c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MURA_ECOLI MURA_ECOLI] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/2z2c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z2c ConSurf].
<div style="clear:both"></div>


'''MURA inhibited by unag-cnicin adduct'''
==See Also==
 
*[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2Z2C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2C OCA].
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
[[Category: Klein CD]]
[[Category: Klein, C D.]]
[[Category: Scheidig AJ]]
[[Category: Scheidig, A J.]]
[[Category: Skarzynski T]]
[[Category: Skarzynski, T.]]
[[Category: Steinbach A]]
[[Category: Steinbach, A.]]
[[Category: Cnicin]]
[[Category: Peptidoglycan]]
[[Category: Transferase]]
[[Category: Udp-n-acetylglucosamine]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 21:45:13 2008''

Latest revision as of 11:08, 23 October 2024

MURA inhibited by unag-cnicin adductMURA inhibited by unag-cnicin adduct

Structural highlights

2z2c is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MURA_ECOLI Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2z2c, resolution 2.05Å

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