3lyz: Difference between revisions

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[[Image:3lyz.jpg|left|200px]]


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==Real-space refinement of the structure of hen egg-white lysozyme==
The line below this paragraph, containing "STRUCTURE_3lyz", creates the "Structure Box" on the page.
<StructureSection load='3lyz' size='340' side='right'caption='[[3lyz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3lyz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LYZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lyz OCA], [https://pdbe.org/3lyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lyz RCSB], [https://www.ebi.ac.uk/pdbsum/3lyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lyz ProSAT]</span></td></tr>
{{STRUCTURE_3lyz| PDB=3lyz |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ly/3lyz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lyz ConSurf].
<div style="clear:both"></div>


'''REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME'''
==See Also==
 
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
 
== References ==
==About this Structure==
<references/>
3LYZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LYZ OCA].
__TOC__
 
</StructureSection>
==Reference==
Real-space refinement of the structure of hen egg-white lysozyme., Diamond R, J Mol Biol. 1974 Jan 25;82(3):371-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/4856347 4856347]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Blake CCF]]
[[Category: Blake, C C.F.]]
[[Category: Diamond R]]
[[Category: Diamond, R.]]
[[Category: North ACT]]
[[Category: North, A C.T.]]
[[Category: Phillips DC]]
[[Category: Phillips, D C.]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:06:24 2008''

Latest revision as of 11:13, 23 October 2024

Real-space refinement of the structure of hen egg-white lysozymeReal-space refinement of the structure of hen egg-white lysozyme

Structural highlights

3lyz is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

3lyz, resolution 2.00Å

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