3cjb: Difference between revisions

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-[[Image:3cjb.jpg|left|200px]]
-<!--
+==Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1==
-The line below this paragraph, containing "STRUCTURE_3cjb", creates the "Structure Box" on the page.
+<StructureSection load='3cjb' size='340' side='right'caption='[[3cjb]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3cjb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CJB FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-{{STRUCTURE_3cjb|  PDB=3cjb  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cjb OCA], [https://pdbe.org/3cjb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cjb RCSB], [https://www.ebi.ac.uk/pdbsum/3cjb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cjb ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cjb_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cjb ConSurf].
+<div style="clear:both"></div>
-'''Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1'''
+==See Also==
+*[[Actin 3D structures|Actin 3D structures]]
+*[[Gelsolin 3D structures|Gelsolin 3D structures]]
-==Disease==
+__TOC__
-Known disease associated with this structure: Amyloidosis, Finnish type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=137350 137350]]
+</StructureSection>
-==About this Structure==
-CJB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJB OCA].
 [[Category: Homo sapiens]]
+[[Category: Large Structures]]
 [[Category: Oryctolagus cuniculus]]
-[[Category: Protein complex]]
+[[Category: Kudryashov DS]]
-[[Category: Kudryashov, D S.]]
+[[Category: Pashkov I]]
-[[Category: Pashkov, I.]]
+[[Category: Reisler E]]
-[[Category: Reisler, E.]]
+[[Category: Sawaya MR]]
-[[Category: Sawaya, M R.]]
+[[Category: Yeates TO]]
-[[Category: Yeates, T O.]]
-[[Category: Acetylation]]
-[[Category: Actin capping]]
-[[Category: Actin-binding]]
-[[Category: Alternative initiation]]
-[[Category: Amyloid]]
-[[Category: Atp-binding]]
-[[Category: Calcium]]
-[[Category: Cross-linked dimer]]
-[[Category: Cytoplasm]]
-[[Category: Cytoskeleton]]
-[[Category: Disease mutation]]
-[[Category: Methylation]]
-[[Category: Muscle protein]]
-[[Category: Nucleotide-binding]]
-[[Category: Phosphoprotein]]
-[[Category: Polymorphism]]
-[[Category: Secreted]]
-[[Category: Structural protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 21:50:05 2008''