2nxu: Difference between revisions

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[[Image:2nxu.gif|left|200px]]


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==Atomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solution==
The line below this paragraph, containing "STRUCTURE_2nxu", creates the "Structure Box" on the page.
<StructureSection load='2nxu' size='340' side='right'caption='[[2nxu]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2nxu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NXU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nxu OCA], [https://pdbe.org/2nxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nxu RCSB], [https://www.ebi.ac.uk/pdbsum/2nxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nxu ProSAT]</span></td></tr>
{{STRUCTURE_2nxu|  PDB=2nxu  |  SCENE= }}
</table>
 
== Function ==
'''Atomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solution'''
[https://www.uniprot.org/uniprot/IF2B_SACS2 IF2B_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00232]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2NXU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXU OCA].  
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nx/2nxu_consurf.spt"</scriptWhenChecked>
==Reference==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
Solution structure of the beta-subunit of the translation initiation factor aIF2 from archaebacteria Sulfolobus solfataricus., Vasile F, Pechkova E, Nicolini C, Proteins. 2008 Feb 15;70(3):1112-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18004773 18004773]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Sulfolobus solfataricus]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nxu ConSurf].
[[Category: Garber, M.]]
<div style="clear:both"></div>
[[Category: Nicolini, C.]]
__TOC__
[[Category: Pechkova, E.]]
</StructureSection>
[[Category: Stolboushkina, E.]]
[[Category: Large Structures]]
[[Category: Vasile, F.]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Aif2beta]]
[[Category: Garber M]]
[[Category: Archaea]]
[[Category: Nicolini C]]
[[Category: Nmr structure]]
[[Category: Pechkova E]]
[[Category: Translation initiation factor]]
[[Category: Stolboushkina E]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:03:03 2008''
[[Category: Vasile F]]

Latest revision as of 03:11, 28 December 2023

Atomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solutionAtomic structure of translation initiation factor aIF2 beta-subunit from Archaebacteria sulfolobus solfataricus: high resolution NMR in solution

Structural highlights

2nxu is a 1 chain structure with sequence from Saccharolobus solfataricus P2. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IF2B_SACS2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00232]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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OCA
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