2oxc: Difference between revisions
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New page: left|200px<br /> <applet load="2oxc" size="450" color="white" frame="true" align="right" spinBox="true" caption="2oxc, resolution 1.30Å" /> '''Human DEAD-box RNA ... |
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== | ==Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP== | ||
<StructureSection load='2oxc' size='340' side='right'caption='[[2oxc]], [[Resolution|resolution]] 1.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2oxc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OXC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxc OCA], [https://pdbe.org/2oxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oxc RCSB], [https://www.ebi.ac.uk/pdbsum/2oxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oxc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DDX20_HUMAN DDX20_HUMAN] The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/2oxc_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oxc ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Berglund H]] | |||
[[Category: Berglund | [[Category: Busam RD]] | ||
[[Category: Busam | [[Category: Collins R]] | ||
[[Category: Collins | [[Category: Dahlgren LG]] | ||
[[Category: Dahlgren | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Flodin S]] | ||
[[Category: Flodin | [[Category: Flores A]] | ||
[[Category: Flores | [[Category: Graslund S]] | ||
[[Category: Graslund | [[Category: Hallberg BM]] | ||
[[Category: Hallberg | [[Category: Hammarstrom M]] | ||
[[Category: Hammarstrom | [[Category: Hogbom M]] | ||
[[Category: Hogbom | [[Category: Holmberg-Schiavone L]] | ||
[[Category: Holmberg-Schiavone | [[Category: Johansson I]] | ||
[[Category: Johansson | [[Category: Karlberg T]] | ||
[[Category: Karlberg | [[Category: Kotenyova T]] | ||
[[Category: Kotenyova | [[Category: Lehtio L]] | ||
[[Category: Lehtio | [[Category: Moche M]] | ||
[[Category: Moche | [[Category: Nordlund P]] | ||
[[Category: Nordlund | [[Category: Nyman T]] | ||
[[Category: Nyman | [[Category: Ogg D]] | ||
[[Category: Ogg | [[Category: Persson C]] | ||
[[Category: Persson | [[Category: Sagemark J]] | ||
[[Category: Stenmark P]] | |||
[[Category: Sagemark | [[Category: Sundstrom M]] | ||
[[Category: Stenmark | [[Category: Thorsell AG]] | ||
[[Category: Sundstrom | [[Category: Van Den Berg S]] | ||
[[Category: Thorsell | [[Category: Weigelt J]] | ||
[[Category: | |||
[[Category: | |||
Latest revision as of 13:49, 30 August 2023
Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADPHuman DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
Structural highlights
FunctionDDX20_HUMAN The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Large Structures
- Arrowsmith CH
- Berglund H
- Busam RD
- Collins R
- Dahlgren LG
- Edwards A
- Flodin S
- Flores A
- Graslund S
- Hallberg BM
- Hammarstrom M
- Hogbom M
- Holmberg-Schiavone L
- Johansson I
- Karlberg T
- Kotenyova T
- Lehtio L
- Moche M
- Nordlund P
- Nyman T
- Ogg D
- Persson C
- Sagemark J
- Stenmark P
- Sundstrom M
- Thorsell AG
- Van Den Berg S
- Weigelt J