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[[Image:2dcg.jpg|left|200px]]


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==MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION==
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<StructureSection load='2dcg' size='340' side='right'caption='[[2dcg]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2dcg]] is a 2 chain structure. The November 2001 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2001_11 10.2210/rcsb_pdb/mom_2001_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DCG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
{{STRUCTURE_2dcg|  PDB=2dcg  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dcg OCA], [https://pdbe.org/2dcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dcg RCSB], [https://www.ebi.ac.uk/pdbsum/2dcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dcg ProSAT]</span></td></tr>
 
</table>
'''MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION'''
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</StructureSection>
 
==Overview==
The DNA fragment d(CpGpCpGpCpG) crystallises as a left-handed double helical molecule with Watson-Crick base pairs and an antiparallel organisation of the sugar phosphate chains. The helix has two nucleotides in the asymmetric unit and contains twelve base pairs per turn. It differs significantly from right-handed B-DNA.
 
==About this Structure==
The following page contains interesting information on the relation of 2DCG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb23_1.html DNA]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCG OCA].  
 
==Reference==
Molecular structure of a left-handed double helical DNA fragment at atomic resolution., Wang AH, Quigley GJ, Kolpak FJ, Crawford JL, van Boom JH, van der Marel G, Rich A, Nature. 1979 Dec 13;282(5740):680-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/514347 514347]
[[Category: DNA]]
[[Category: DNA]]
[[Category: Boom, J H.Van.]]
[[Category: Large Structures]]
[[Category: Crawford, J L.]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Kolpak, F J.]]
[[Category: Crawford JL]]
[[Category: Marel, G A.Van Der.]]
[[Category: Kolpak FJ]]
[[Category: Quigley, G J.]]
[[Category: Quigley GJ]]
[[Category: Rich, A.]]
[[Category: Rich A]]
[[Category: Wang, A H.J.]]
[[Category: Van Boom JH]]
[[Category: Double helix]]
[[Category: Van Der Marel GA]]
[[Category: Z-dna]]
[[Category: Wang AH-J]]
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