User:Ann Taylor/GLP-1 agonists: Difference between revisions

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New page: ==GLP-1 agonists== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> Glucagon-like peptide agonists (GLP) are used to treat type 2 diabe...
 
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==GLP-1 agonists==
==GLP-1 agonists==
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='5NX2' size='340' side='right' caption='GLP-1 bound to receptor complex'>


Glucagon-like peptide agonists (GLP) are used to treat type 2 diabetes and obesity <ref>PMID:38639549</ref>.
<scene name='10/1043704/Glp-1_peptide/1'>Glucagon-like peptide agonists</scene> (GLP) are used to treat type 2 diabetes and obesity <ref>PMID:38639549</ref>. They GLP-1 agonists bind to the GLP receptor.


The GLP receptor is a G-protein coupled receptor.  Its secondary structure is highlighted in <scene name='10/1043704/Glpr_secondary/1'>this view</scene>. The hydrophobic residues are shown in grey and the polar residues are shown in magenta in <scene name='10/1043704/Glpr_hydrophobic_hydrophilic/1'>this view</scene>.


</StructureSection>


</StructureSection>
== References ==
== References ==
<references/>
<references/>

Latest revision as of 23:14, 5 December 2024

GLP-1 agonistsGLP-1 agonists


(GLP) are used to treat type 2 diabetes and obesity [1]. They GLP-1 agonists bind to the GLP receptor.

The GLP receptor is a G-protein coupled receptor. Its secondary structure is highlighted in . The hydrophobic residues are shown in grey and the polar residues are shown in magenta in .


GLP-1 bound to receptor complex

Drag the structure with the mouse to rotate

ReferencesReferences

  1. Drake T, Landsteiner A, Langsetmo L, MacDonald R, Anthony M, Kalinowski C, Ullman K, Billington CJ, Kaka A, Sultan S, Wilt TJ. Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-analysis for the American College of Physicians. Ann Intern Med. 2024 Apr 19. PMID:38639549 doi:10.7326/M23-1490