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==CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455 and Inhibitor MC4741== | |||
<StructureSection load='8vph' size='340' side='right'caption='[[8vph]], [[Resolution|resolution]] 3.18Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8vph]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile Clostridioides difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VPH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.18Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AC7:~{N}-[3-[(2-azanyl-6-methyl-pyrimidin-4-yl)amino]-5-[(dimethylamino)methyl]phenyl]-3-(quinolin-4-ylamino)benzamide'>A1AC7</scene>, <scene name='pdbligand=Q8Y:N-(3-phenylpropyl)adenosine'>Q8Y</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vph OCA], [https://pdbe.org/8vph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vph RCSB], [https://www.ebi.ac.uk/pdbsum/8vph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vph ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A031WG99_CLODI A0A031WG99_CLODI] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Clostridioides difficile]] | |||
[[Category: Large Structures]] | |||
[[Category: Cheng X]] | |||
[[Category: Horton JR]] | |||
[[Category: Zhou J]] | |||
Latest revision as of 07:11, 5 October 2024
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455 and Inhibitor MC4741CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455 and Inhibitor MC4741
Structural highlights
Function |
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