Signal recognition particle receptor: Difference between revisions

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*<scene name='48/485587/Cv/6'>GTP binding site</scene>. Water molecules are shown as red spheres.
*<scene name='48/485587/Cv/6'>GTP binding site</scene>. Water molecules are shown as red spheres.
*<scene name='48/485587/Cv/7'>Mg coordination site</scene>.
*<scene name='48/485587/Cv/7'>Mg coordination site</scene>.
</StructureSection>
 
==3D structures of signal recognition particle receptor==
==3D structures of signal recognition particle receptor==


[[Signal recognition particle receptor 3D structures]]
[[Signal recognition particle receptor 3D structures]]
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*Signal recognition particle receptor
**[[2fh5]] - hSRPR α+β subunits + GTP – human<br />
**[[6y32]] - hSRPR α subunit + SRP54 + GNP <br />
**[[5l3q]] - hSRPR α subunit + SRP54 + AMP + GNP <br />
**[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - Cryo EM<br />
**[[7obq]] - rSRPR α+b subunits + dSRP19 + dSRP54 + dSRP68 + dSRP72 + RNA – rabbit - Cryo EM<br />
**[[7nfx]] - rSRPR α+b subunits in human ribosome - Cryo EM<br />
**[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
**[[2ged]] - ySRPR β subunit (mutant)<br />
*Signal recognition particle receptor FtsY; Domain NG 195-498
**[[3jaj]], [[3jan]] – FtsY in ribosome - rabbit - Cryo EM<br />
**[[5l3r]] – SRPR FtsY + SRP54 - ''Arabidopsis thaliana''<br />
**[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
**[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
**[[6cy1]] – EaSRPR FtsY – ''Elizabethkingia anopheles''<br />
**[[6cy5]] – EaSRPR FtsY NG domain + GDP<br />
**[[2q9a]] – TaSRPR FtsY – ''Thermus aquaticus''<br />
**[[2q9c]], [[2q9b]] – TaSRPR FtsY NG domain + GMPPNP<br />
**[[2j7p]], [[1rj9]], [[1okk]] – TaSRPR FtsY NG domain + SRP <br />
**[[2cnw]] – TaSRPR FtsY NG domain + SRP + GDP<br />
**[[5niy]] – EcSRPR FtsY – ''Escherichia coli''<br />
**[[6fpk]], [[6fpr]] – EcSRPR FtsY N-terminal<br />
**[[2yhs]], [[2qy9]], [[1fts]], [[6cqp]], [[6cs8]], [[6n5i]], [[6n5j]], [[6n6n]], [[6n9b]], [[6nc1]], [[6nc4]] – EcSRPR FtsY NG domain<br />
**[[6fqd]] – EcSRPR FtsY NG domain + GDP<br />
**[[7o9h]] – EcSRPR FtsY NG domain + pppGpp<br />
**[[6c58]], [[6cvd]], [[6dlx]] – EcSRPR FtsY NG domain + antibiotic<br />
**[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
**[[2xxa]] - EcSRPR FtsY NG domain + SRP residues 1-433 (mutant) + 4.5SRNA<br />
**[[3zn8]] - EcSRPR FtsY NG domain + SRP54 NG domain + 4.5SRNA + dipeptidyl aminopeptidase B<br />
**[[4c7o]] – EcFtsY + EcSRP + SRP RNA<br />
**[[2xkv]] – EcFtsY + EcSRP NG+M domains + 4.5S RNA<br />
**[[5aka]], [[5gad]], [[5nco]], [[5gaf]], [[5gag]], [[5gah]] – EcFtsY in ribosome - Cryo EM<br />
**[[5l3w]] – SRPR FtsY NG domain - ''Sulfolobus acidocaldarius''<br />
**[[5l3s]] – SRPR FtsY + SRP54 + GNP - ''Sulfolobus solfataricus''<br />
**[[3dm9]], [[3dmd]], [[3e70]] – SRPR + GDP – ''Pyrococcus furiosus''
}}


</StructureSection>  
</StructureSection>  
[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 13:31, 20 November 2023


Signal recognition particle receptor (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the signal recognition particle (SRP). SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called FtsY.

See also Intracellular receptors

  • . Water molecules are shown as red spheres.
  • .

3D structures of signal recognition particle receptor

Signal recognition particle receptor 3D structures


Human SRPR α (magenta) and β subunit (deepskyblue) complex with GTP and Mg+2 (green) ion 2fh5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman