8jun: Difference between revisions

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Latest revision as of 16:52, 24 January 2024

Cryo-EM structure of SIDT1 E555Q mutantCryo-EM structure of SIDT1 E555Q mutant

Structural highlights

8jun is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.38Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SIDT1_HUMAN In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.[UniProtKB:Q6AXF6]

8jun, resolution 2.38Å

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OCA