8qb9: Difference between revisions
Jump to navigation
Jump to search
New page: '''Unreleased structure''' The entry 8qb9 is ON HOLD Authors: Kefauver, J.M., Zou, L., Desfosses, A., Loewith, R.J. Description: Helical reconstruction of yeast eisosome protein Pil1 b... |
No edit summary |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)== | |||
<StructureSection load='8qb9' size='340' side='right'caption='[[8qb9]], [[Resolution|resolution]] 3.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8qb9]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QB9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.35Å</td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qb9 OCA], [https://pdbe.org/8qb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qb9 RCSB], [https://www.ebi.ac.uk/pdbsum/8qb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qb9 ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[[Category: | == Function == | ||
[[Category: Desfosses | [https://www.uniprot.org/uniprot/PIL1_YEAST PIL1_YEAST] Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase PKH1/PHK2 activity and regulating their downstream CWI pathways PKC1-MAP kinase pathway and protein kinase YPK1 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress.<ref>PMID:15016821</ref> | ||
[[Category: Kefauver | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Desfosses A]] | |||
[[Category: Kefauver JM]] | |||
[[Category: Loewith RJ]] | |||
[[Category: Zou L]] | |||
Latest revision as of 09:31, 24 July 2024
Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)
Structural highlights
FunctionPIL1_YEAST Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase PKH1/PHK2 activity and regulating their downstream CWI pathways PKC1-MAP kinase pathway and protein kinase YPK1 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress.[1] References
|
| ||||||||||||||||