Nucleoside triphosphatase: Difference between revisions
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< | <StructureSection load='4a5a' size='350' side='right' caption='NTPase 2 tetramer complex with AMPPNP and Mg++ ion (green) (PDB entry [[4a5a]])' scene=''> | ||
== Function == | == Function == | ||
'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown<ref>PMID:24115522</ref>. | '''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown<ref>PMID:24115522</ref>. | ||
*'''Nucleoside triphosphatase Nudi''' catalyses the hydrolysis of preferentially dUTP, dTTP and dCTP. | |||
== Relevance == | == Relevance == | ||
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*<snapshot name='84/844927/Cv1/6'>Test2</snapshot> | *<snapshot name='84/844927/Cv1/6'>Test2</snapshot> | ||
*<snapshot name='84/844927/Cv1/8'>Test3</snapshot> | *<snapshot name='84/844927/Cv1/8'>Test3</snapshot> | ||
==3D structures of nucleoside triphosphatase== | ==3D structures of nucleoside triphosphatase== | ||
[[Nucleoside triphosphatase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||