5hca: Difference between revisions
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== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ | [https://www.uniprot.org/uniprot/CALR_ENTH1 CALR_ENTH1] Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle (By similarity). This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Plays a role in host cell phagocytosis, possibly by acting as a receptor for host C1q (PubMed:22473608). Binding to C1q prevents the activation of the host classical complement pathway (PubMed:24860808). Also, binds to apoptotic host cells independently of host C1q and collectins (PubMed:22473608).[UniProtKB:P27797]<ref>PMID:22473608</ref> <ref>PMID:24860808</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||