8de4: Difference between revisions

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== Function ==
== Function ==
[https://www.uniprot.org/uniprot/A0A4X1TV69_PIG A0A4X1TV69_PIG] Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.[ARBA:ARBA00025296]
[https://www.uniprot.org/uniprot/F1RN70_PIG F1RN70_PIG]  
 
==See Also==
*[[Serotonin Transporter|Serotonin Transporter]]
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</StructureSection>
</StructureSection>

Latest revision as of 15:02, 23 October 2024

Native serotonin transporter in complex with 15B8 Fab in the presence of methamphetamineNative serotonin transporter in complex with 15B8 Fab in the presence of methamphetamine

Structural highlights

8de4 is a 3 chain structure with sequence from Mus musculus and Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.9Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

F1RN70_PIG

See Also

8de4, resolution 2.90Å

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OCA
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