8jad: Difference between revisions

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-'''Unreleased structure'''
-The entry 8jad is ON HOLD  until Paper Publication
+==Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-17==
+<StructureSection load='8jad' size='340' side='right'caption='[[8jad]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Zhang, B., Liang, J., Rao, Z.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8jad]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JAD FirstGlance]. <br>
-Description: Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-17
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Zhang, B]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jad OCA], [https://pdbe.org/8jad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jad RCSB], [https://www.ebi.ac.uk/pdbsum/8jad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jad ProSAT]</span></td></tr>
-[[Category: Liang, J]]
+</table>
-[[Category: Rao, Z]]
+== Function ==
+[https://www.uniprot.org/uniprot/LPQY_MYCTU LPQY_MYCTU] Part of the ABC transporter complex LpqY-SugA-SugB-SugC, which is highly specific for uptake of trehalose. Involved in the recycling of extracellular trehalose released from trehalose-containing molecules synthesized by M.tuberculosis. Trehalose uptake is essential for virulence.<ref>PMID:21118978</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
+[[Category: Liang J]]
+[[Category: Rao Z]]
+[[Category: Zhang B]]