4zb3: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZB3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZB3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zb3 OCA], [https://pdbe.org/4zb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zb3 RCSB], [https://www.ebi.ac.uk/pdbsum/4zb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zb3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zb3 OCA], [https://pdbe.org/4zb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zb3 RCSB], [https://www.ebi.ac.uk/pdbsum/4zb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zb3 ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 12:04, 20 March 2024

Crystal structure of the apo AtNUDT7Crystal structure of the apo AtNUDT7

Structural highlights

4zb3 is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUDT7_ARATH Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8-oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling.[1] [2] [3] [4] [5]

See Also

References

  1. ↑ Ogawa T, Ueda Y, Yoshimura K, Shigeoka S. Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana. J Biol Chem. 2005 Jul 1;280(26):25277-83. Epub 2005 May 5. PMID:15878881 doi:http://dx.doi.org/M503536200
  2. ↑ Olejnik K, Kraszewska E. Cloning and characterization of an Arabidopsis thaliana Nudix hydrolase homologous to the mammalian GFG protein. Biochim Biophys Acta. 2005 Sep 25;1752(2):133-41. PMID:16154395 doi:http://dx.doi.org/10.1016/j.bbapap.2005.07.021
  3. ↑ Jambunathan N, Mahalingam R. Analysis of Arabidopsis growth factor gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling. Planta. 2006 Jun;224(1):1-11. Epub 2005 Dec 3. PMID:16328543 doi:http://dx.doi.org/10.1007/s00425-005-0183-y
  4. ↑ Bartsch M, Gobbato E, Bednarek P, Debey S, Schultze JL, Bautor J, Parker JE. Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell. 2006 Apr;18(4):1038-51. Epub 2006 Mar 10. PMID:16531493 doi:http://dx.doi.org/tpc.105.039982
  5. ↑ Ge X, Li GJ, Wang SB, Zhu H, Zhu T, Wang X, Xia Y. AtNUDT7, a negative regulator of basal immunity in Arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol. 2007 Sep;145(1):204-15. Epub 2007 Jul 27. PMID:17660350 doi:http://dx.doi.org/pp.107.103374

4zb3, resolution 2.30Å

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