8sbu: Difference between revisions

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'''Unreleased structure'''


The entry 8sbu is ON HOLD
==Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii==
 
<StructureSection load='8sbu' size='340' side='right'caption='[[8sbu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8sbu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SBU FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sbu OCA], [https://pdbe.org/8sbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sbu RCSB], [https://www.ebi.ac.uk/pdbsum/8sbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sbu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/MPTE_METJA MPTE_METJA] Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).[HAMAP-Rule:MF_02131]<ref>PMID:22931285</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii DSM 2661]]
[[Category: Cherry S]]
[[Category: Ji X]]
[[Category: Needle D]]
[[Category: Shaw GX]]
[[Category: Stair NR]]
[[Category: Tropea JE]]
[[Category: Waugh DS]]

Latest revision as of 10:17, 3 July 2024

Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschiiCrystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii

Structural highlights

8sbu is a 2 chain structure with sequence from Escherichia coli K-12 and Methanocaldococcus jannaschii DSM 2661. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MALE_ECOLI Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.MPTE_METJA Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).[HAMAP-Rule:MF_02131][1]

References

  1. de Crecy-Lagard V, Phillips G, Grochowski LL, El Yacoubi B, Jenney F, Adams MW, Murzin AG, White RH. Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate. ACS Chem Biol. 2012 Nov 16;7(11):1807-16. doi: 10.1021/cb300342u. Epub 2012 Sep, 7. PMID:22931285 doi:http://dx.doi.org/10.1021/cb300342u

8sbu, resolution 2.20Å

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