8i3b: Difference between revisions

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New page: '''Unreleased structure''' The entry 8i3b is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 8i3b is ON HOLD
==Cryo-EM structure of abscisic acid transporter AtABCG25 in nanodisc==
 
<StructureSection load='8i3b' size='340' side='right'caption='[[8i3b]], [[Resolution|resolution]] 3.08&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8i3b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I3B FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.08&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i3b OCA], [https://pdbe.org/8i3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i3b RCSB], [https://www.ebi.ac.uk/pdbsum/8i3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i3b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AB25G_ARATH AB25G_ARATH] High affinity abscisic acid (ABA) transporter that mediates the export of ABA, with a preference for (+)-ABA, through the plasma membrane, especially in vascular tissues (e.g. phloem companion cells), and is involved in the intercellular ABA signaling pathway (PubMed:20133881, PubMed:20935463, PubMed:24521878, PubMed:26517905). Together with ABCG31, export ABA from the endosperm to deliver it to the embryo via ABCG30 and ABCG40-mediated import to suppress radicle extension and subsequent embryonic growth (PubMed:26334616).<ref>PMID:20133881</ref> <ref>PMID:24521878</ref> <ref>PMID:26334616</ref> <ref>PMID:20935463</ref> <ref>PMID:26517905</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Huang X]]
[[Category: Zhang P]]
[[Category: Zhang X]]

Latest revision as of 14:18, 14 March 2024

Cryo-EM structure of abscisic acid transporter AtABCG25 in nanodiscCryo-EM structure of abscisic acid transporter AtABCG25 in nanodisc

Structural highlights

8i3b is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.08Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AB25G_ARATH High affinity abscisic acid (ABA) transporter that mediates the export of ABA, with a preference for (+)-ABA, through the plasma membrane, especially in vascular tissues (e.g. phloem companion cells), and is involved in the intercellular ABA signaling pathway (PubMed:20133881, PubMed:20935463, PubMed:24521878, PubMed:26517905). Together with ABCG31, export ABA from the endosperm to deliver it to the embryo via ABCG30 and ABCG40-mediated import to suppress radicle extension and subsequent embryonic growth (PubMed:26334616).[1] [2] [3] [4] [5]

References

  1. Kuromori T, Miyaji T, Yabuuchi H, Shimizu H, Sugimoto E, Kamiya A, Moriyama Y, Shinozaki K. ABC transporter AtABCG25 is involved in abscisic acid transport and responses. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2361-6. PMID:20133881 doi:10.1073/pnas.0912516107
  2. Kuromori T, Sugimoto E, Shinozaki K. Intertissue signal transfer of abscisic acid from vascular cells to guard cells. Plant Physiol. 2014 Apr;164(4):1587-92. PMID:24521878 doi:10.1104/pp.114.235556
  3. Kang J, Yim S, Choi H, Kim A, Lee KP, Lopez-Molina L, Martinoia E, Lee Y. Abscisic acid transporters cooperate to control seed germination. Nat Commun. 2015 Sep 3;6:8113. PMID:26334616 doi:10.1038/ncomms9113
  4. Kuromori T, Shinozaki K. ABA transport factors found in Arabidopsis ABC transporters. Plant Signal Behav. 2010 Sep;5(9):1124-6. PMID:20935463 doi:10.4161/psb.5.9.12566
  5. Borghi L, Kang J, Ko D, Lee Y, Martinoia E. The role of ABCG-type ABC transporters in phytohormone transport. Biochem Soc Trans. 2015 Oct;43(5):924-30. PMID:26517905 doi:10.1042/BST20150106

8i3b, resolution 3.08Å

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