DNA mismatch repair protein: Difference between revisions
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'''DNA mismatch repair proteins''' are key players in genomic stability by signalling mismatches occurring during DNA replication and recombination<ref>PMID:18157157</ref> .<br/> | '''DNA mismatch repair proteins''' are key players in genomic stability by signalling mismatches occurring during DNA replication and recombination<ref>PMID:18157157</ref> .<br/> | ||
'''MutS''' is prokaryotic and recognizes base-base mismatches and small insertion/deletion mispairs<ref>PMID:11048711</ref> .<br /> | *'''MutS''' is prokaryotic and recognizes base-base mismatches and small insertion/deletion mispairs<ref>PMID:11048711</ref> .<br /> | ||
'''MutL''' enhances recognition of mismatches<ref>PMID:15470502</ref> <br /> | *'''MutL''' enhances recognition of mismatches<ref>PMID:15470502</ref> <br /> | ||
'''MutH''' is the eukaryotic homolog of MutS. See also [[DNA Repair]] <br /> | *'''MutH''' is the eukaryotic homolog of MutS. See also [[DNA Repair]] <br /> | ||
'''MLH1, MLH3, PMS1, PMS2''' are the human homologs of MutL<ref>PMID:15475387</ref> <br /> | *'''MLH1, MLH3, PMS1, PMS2''' are the human homologs of MutL<ref>PMID:15475387</ref> <br /> | ||
== Disease == | == Disease == | ||