8b4d: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 8b4d is ON HOLD
+==ToxR bacterial transcriptional regulator bound to 40 bp toxT promoter DNA==
+<StructureSection load='8b4d' size='340' side='right'caption='[[8b4d]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8b4d]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B4D FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b4d OCA], [https://pdbe.org/8b4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b4d RCSB], [https://www.ebi.ac.uk/pdbsum/8b4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b4d ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TOXR_VIBCH TOXR_VIBCH] This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.
-Authors:
+==See Also==
+*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
-Description:
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Vibrio cholerae]]
+[[Category: Canals A]]
+[[Category: Coll M]]
+[[Category: El Yaman N]]
+[[Category: Fabrega-Ferrer M]]
+[[Category: Krukonis ES]]
+[[Category: Muriel M]]
+[[Category: Perez-Luque R]]
+[[Category: Pieretti S]]