8br9: Difference between revisions
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New page: '''Unreleased structure''' The entry 8br9 is ON HOLD Authors: Pantelejevs, T., Hyvonen, M. Description: Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22 [[Category:... |
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==Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22== | |||
<StructureSection load='8br9' size='340' side='right'caption='[[8br9]], [[Resolution|resolution]] 1.63Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8br9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BR9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RF6:4,6-diethylpyrimidin-2-amine'>RF6</scene></td></tr> | ||
[[Category: Hyvonen | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8br9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8br9 OCA], [https://pdbe.org/8br9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8br9 RCSB], [https://www.ebi.ac.uk/pdbsum/8br9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8br9 ProSAT]</span></td></tr> | ||
[[Category: Pantelejevs | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus furiosus]] | |||
[[Category: Hyvonen M]] | |||
[[Category: Pantelejevs T]] | |||
Latest revision as of 03:57, 28 December 2023
Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22
Structural highlights
FunctionRADA_PYRFU Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. |
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