8f11: Difference between revisions
New page: '''Unreleased structure''' The entry 8f11 is ON HOLD Authors: Wilson, M.A., Madzelan, P., Rajca, A., Stein, R., Yang, Z. Description: T4 lysozyme with a 2,6-diazaadamantane nitroxide (... |
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==T4 lysozyme with a 2,6-diazaadamantane nitroxide (DZD) spin label== | |||
<StructureSection load='8f11' size='340' side='right'caption='[[8f11]], [[Resolution|resolution]] 1.12Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8f11]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T4 Escherichia phage T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F11 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=X8R:1-[(1r,3r,5r,7r)-6-hydroxy-2,6-diazatricyclo[3.3.1.1~3,7~]decan-2-yl]ethan-1-one'>X8R</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f11 OCA], [https://pdbe.org/8f11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f11 RCSB], [https://www.ebi.ac.uk/pdbsum/8f11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f11 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A7S9SVX7_BPT4 A0A7S9SVX7_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.[HAMAP-Rule:MF_04110] | |||
==See Also== | |||
*[[Lysozyme 3D structures|Lysozyme 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Madzelan | [[Category: Escherichia phage T4]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Madzelan P]] | ||
[[Category: Wilson | [[Category: Rajca A]] | ||
[[Category: | [[Category: Stein R]] | ||
[[Category: Wilson MA]] | |||
[[Category: Yang Z]] | |||