7vrk: Difference between revisions

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-'''Unreleased structure'''
-The entry 7vrk is ON HOLD  until 2024-01-26
+==crystal structure of BRD2-BD1 in complex with purine derivative==
+<StructureSection load='7vrk' size='340' side='right'caption='[[7vrk]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
-Authors: Padmanabhan, B., Arole, A., Deshmukh, P., Ashok, S., Mathur, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7vrk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VRK FirstGlance]. <br>
-Description: crystal structure of BRD2-BD1 in complex with purine derivative
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TEP:THEOPHYLLINE'>TEP</scene></td></tr>
-[[Category: Mathur, S]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vrk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vrk OCA], [https://pdbe.org/7vrk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vrk RCSB], [https://www.ebi.ac.uk/pdbsum/7vrk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vrk ProSAT]</span></td></tr>
-[[Category: Padmanabhan, B]]
+</table>
-[[Category: Ashok, S]]
+== Function ==
-[[Category: Deshmukh, P]]
+[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
-[[Category: Arole, A]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Arole A]]
+[[Category: Ashok S]]
+[[Category: Deshmukh P]]
+[[Category: Mathur S]]
+[[Category: Padmanabhan B]]