8b22: Difference between revisions

Latest revision as of 13:02, 17 January 2024

Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+

Structural highlights

8b22 is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.98Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HPPA_THEMA Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.[HAMAP-Rule:MF_01129]^[1] ^[2] ^[3]

References

↑ Perez-Castineira JR, Lopez-Marques RL, Losada M, Serrano A. A thermostable K(+)-stimulated vacuolar-type pyrophosphatase from the hyperthermophilic bacterium Thermotoga maritima. FEBS Lett. 2001 May 4;496(1):6-11. PMID:11343697
↑ Malinen AM, Belogurov GA, Baykov AA, Lahti R. Na+-pyrophosphatase: a novel primary sodium pump. Biochemistry. 2007 Jul 31;46(30):8872-8. Epub 2007 Jul 3. PMID:17605473 doi:http://dx.doi.org/10.1021/bi700564b
↑ Kellosalo J, Kajander T, Kogan K, Pokharel K, Goldman A. The structure and catalytic cycle of a sodium-pumping pyrophosphatase. Science. 2012 Jul 27;337(6093):473-6. PMID:22837527 doi:10.1126/science.1222505

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OCA

[1] Perez-Castineira JR, Lopez-Marques RL, Losada M, Serrano A. A thermostable K(+)-stimulated vacuolar-type pyrophosphatase from the hyperthermophilic bacterium Thermotoga maritima. FEBS Lett. 2001 May 4;496(1):6-11. PMID:11343697

[2] Malinen AM, Belogurov GA, Baykov AA, Lahti R. Na+-pyrophosphatase: a novel primary sodium pump. Biochemistry. 2007 Jul 31;46(30):8872-8. Epub 2007 Jul 3. PMID:17605473 doi:http://dx.doi.org/10.1021/bi700564b

[3] Kellosalo J, Kajander T, Kogan K, Pokharel K, Goldman A. The structure and catalytic cycle of a sodium-pumping pyrophosphatase. Science. 2012 Jul 27;337(6093):473-6. PMID:22837527 doi:10.1126/science.1222505

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8b22 is ON HOLD
+==Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+==
+<StructureSection load='8b22' size='340' side='right'caption='[[8b22]], [[Resolution|resolution]] 3.98&Aring;' scene=''>
-Authors: Strauss, J., Vidilaseris, K., Goldman, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8b22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B22 FirstGlance]. <br>
-Description: The structure of TmPPase after 300 second soaking with sodium ion
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.98&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Goldman, A]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b22 OCA], [https://pdbe.org/8b22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b22 RCSB], [https://www.ebi.ac.uk/pdbsum/8b22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b22 ProSAT]</span></td></tr>
-[[Category: Strauss, J]]
+</table>
-[[Category: Vidilaseris, K]]
+== Function ==
+[https://www.uniprot.org/uniprot/HPPA_THEMA HPPA_THEMA] Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.[HAMAP-Rule:MF_01129]<ref>PMID:11343697</ref> <ref>PMID:17605473</ref> <ref>PMID:22837527</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Thermotoga maritima]]
+[[Category: Goldman A]]
+[[Category: Strauss J]]
+[[Category: Vidilaseris K]]

8b22: Difference between revisions

Latest revision as of 13:02, 17 January 2024

Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+

Structural highlights

Function

References

Contents

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8b22: Difference between revisions

Latest revision as of 13:02, 17 January 2024

Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+Time-resolved structure of K+-dependent Na+-PPase from Thermotoga maritima 300-seconds post reaction initiation with Na+

Structural highlights

Function

References

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