8e9i: Difference between revisions

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-'''Unreleased structure'''
-The entry 8e9i is ON HOLD
+==Mycobacterial respiratory complex I, semi-inserted quinone==
+<StructureSection load='8e9i' size='340' side='right'caption='[[8e9i]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors: Liang, Y., Rubinstein, J.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8e9i]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E9I FirstGlance]. <br>
-Description: Mycobacterial respiratory complex I, semi-inserted quinone
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MQ9:MENAQUINONE-9'>MQ9</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=XP2:(2R)-3-{[(R)-hydroxy({(1S,2R,3R,4R,5S,6S)-3,4,5-trihydroxy-2-(alpha-D-mannopyranosyloxy)-6-[(6-O-undecanoyl-beta-D-mannopyranosyl)oxy]cyclohexyl}oxy)phosphoryl]oxy}-2-(octanoyloxy)propyl+undecanoate'>XP2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Rubinstein, J.L]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e9i OCA], [https://pdbe.org/8e9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e9i RCSB], [https://www.ebi.ac.uk/pdbsum/8e9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e9i ProSAT]</span></td></tr>
-[[Category: Liang, Y]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0QU23_MYCS2 A0QU23_MYCS2] NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.[HAMAP-Rule:MF_00445]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mycolicibacterium smegmatis MC2 155]]
+[[Category: Liang Y]]
+[[Category: Rubinstein JL]]