4avp: Difference between revisions
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<StructureSection load='4avp' size='340' side='right'caption='[[4avp]], [[Resolution|resolution]] 1.82Å' scene=''> | <StructureSection load='4avp' size='340' side='right'caption='[[4avp]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4avp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4avp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AVP FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4avp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4avp OCA], [https://pdbe.org/4avp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4avp RCSB], [https://www.ebi.ac.uk/pdbsum/4avp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4avp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4avp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4avp OCA], [https://pdbe.org/4avp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4avp RCSB], [https://www.ebi.ac.uk/pdbsum/4avp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4avp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/ETV1_HUMAN ETV1_HUMAN] Ewing sarcoma. Ewing sarcoma (ES) [MIM:[https://omim.org/entry/612219 612219]: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ETV1_HUMAN ETV1_HUMAN] Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Allerston | [[Category: Allerston CK]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Canning | [[Category: Canning P]] | ||
[[Category: Chaikuad | [[Category: Chaikuad A]] | ||
[[Category: Cooper | [[Category: Cooper CDO]] | ||
[[Category: Edwards A]] | |||
[[Category: Edwards | [[Category: Filippakopoulos P]] | ||
[[Category: Filippakopoulos | [[Category: Gileadi O]] | ||
[[Category: Gileadi | [[Category: Krojer T]] | ||
[[Category: Krojer | [[Category: Von Delft F]] | ||
[[Category: | |||