4a9h: Difference between revisions

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<StructureSection load='4a9h' size='340' side='right'caption='[[4a9h]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4a9h' size='340' side='right'caption='[[4a9h]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a9h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A9H FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a9h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A9H FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TVP:(2S)-1-ACETYL-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINE'>TVP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yek|2yek]], [[4a9e|4a9e]], [[1x0j|1x0j]], [[4a9f|4a9f]], [[2ydw|2ydw]], [[4a9k|4a9k]], [[4a9j|4a9j]], [[4a9m|4a9m]], [[4a9o|4a9o]], [[4a9l|4a9l]], [[4a9p|4a9p]], [[4a9n|4a9n]], [[4a9i|4a9i]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TVP:(2S)-1-ACETYL-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINE'>TVP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a9h OCA], [https://pdbe.org/4a9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a9h RCSB], [https://www.ebi.ac.uk/pdbsum/4a9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a9h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a9h OCA], [https://pdbe.org/4a9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a9h RCSB], [https://www.ebi.ac.uk/pdbsum/4a9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a9h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bamborough, P]]
[[Category: Bamborough P]]
[[Category: Chung, C W]]
[[Category: Chung CW]]
[[Category: Epigenetic reader]]
[[Category: Histone]]
[[Category: Inhibitor]]
[[Category: Signaling protein]]

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