8e0c: Difference between revisions

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-'''Unreleased structure'''
-The entry 8e0c is ON HOLD  until Paper Publication
+==Crystal structure of human Sar1bH79G==
+<StructureSection load='8e0c' size='340' side='right'caption='[[8e0c]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
-Authors: Huang, Q.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8e0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E0C FirstGlance]. <br>
-Description: Crystal structure of human Sar1bH79G
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.993&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Huang, Q]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e0c OCA], [https://pdbe.org/8e0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e0c RCSB], [https://www.ebi.ac.uk/pdbsum/8e0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e0c ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/SAR1B_HUMAN SAR1B_HUMAN] Chylomicron retention disease. The disease is caused by variants affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/SAR1B_HUMAN SAR1B_HUMAN] GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Activated by the guanine nucleotide exchange factor PREB (By similarity). Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis (PubMed:33186557).[UniProtKB:Q9QVY3]<ref>PMID:33186557</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Huang Q]]